James Alexander Stock Pharmaceuticals

Indications

Amyl Nitrite Inhalant USP is an organic nitrite used for the relief and prophylactic management of angina pectoris. The drug is delivered via inhalation.

Pharmacology

The principal pharmacological action of Amyl Nitrite is relaxation of vascular smooth muscle, resulting in generalized vasodilation. Although Amyl Nitrite reflexly increases heart rate and myocardial contractility which increases myocardial oxygen consumption, the reduction in ventricular wall tension results in a net decrease in myocardial oxygen consumption. By decreasing myocardial oxygen consumption, Amyl Nitrite alters the imbalance of myocardial oxygen supply which causes angina pectoris.

Product Stability

James Alexander’s Amyl Nitrite Inhalant USP carries an expiration date of three years.

Product Storage Conditions

Keep protected from light at 2-8 degrees C (36-46 degrees F). Amyl Nitrite is extremely flammable. Keep from heat and open flame.

Directions for Use

The inhalant should be held away from the face while activating the package. To break the inner vial, crush ONCE between the thumb and forefinger at the dot located at the center of the inhalant. Carefully pass the inhalant back and forth close to the nose of the affected person several times. Discard inhalant after use. Relief usually occurs in one to three minutes.

Precautions

Amyl Nitrite Inhalant is a prescription drug. Use only in accordance with a physician’s instructions. FDA regulations specifically prohibit labeling the product for uses other than the treatment of angina pectoris (see 21CFR 250.102)

James Alexander’s Product Configuration and Packaging

JAC offers Amyl Nitrite Inhalant USP as a unit dose inhalant containing 0.3 mls. The inhalants are packaged in the following configurations:

• James Alexander’s Product Code G-2201 – bulk Amyl Nitrite Inhalants USP. Packaged 15,000 units per shipping carton.
• James Alexander’s Code 22101 – 12 individual boxes of 12 inhalants packaged in a carton. Packaged 264 boxes per shipping

Safety Data Sheet | Pricing

Product Description

James Alexander Corporation’s Ammonia Inhalant Solution is a proprietary formulation used to prevent or treat fainting.

Active Ingredients

The active ingredient in Ammonia Inhalant is Strong Ammonia Solution NF. The formulation is precisely adjusted to yield an ammonia concentration of 18.5% w/w. The formulation also contains 35.0-40.0% v/v Dehydrated Alcohol USP.

Federal Government Specifications

James Alexander’s Ammonia Inhalants fully meet the U.S. Government’s specification number U-A-500B dated March 30, 1976 for Aromatic Ammonia Inhalants.

Product Stability

James Alexander’s Ammonia Inhalants carry a five (5) year expiration date, the maximum allowed by the Food and Drug Administration.

Directions For Use

Ammonia Inhalants are used for inhalation only to prevent or treat fainting. The inhalant should be held away from the face while activating the package. To break the inner vial, crush ONCE between the thumb and forefinger at the dot located at the center of the inhalant. Pass the inhalant back and forth close to the nose of the affected person several times. If the condition persists, consult a physician. Discard inhalant after use. Caution-Ammonia Inhalant formulation is flammable. Keep away from heat and open flame.

JAC Product Configuration and Packaging

James Alexander’s Ammonia Inhalants are offered as a unit dose inhalant containing 0.3 mls of solution in the following packaging options:

• James Alexander Product Code G-3301– bulk unit dose Inhalants. Packaged 15,000 units per shipping carton.
• James Alexander Code 33201- inhalants packaged 100 per box.
• James Alexander Code 33301- inhalants packaged 10 per box (designed for use in first aid kits).

Safety Data Sheet | Pricing | Drug Facts

Product Description

Povidone iodine topical solution USP (PVP) is an aqueous formulation of povidone-iodine, a compound formed by heating 1-vinyl-2-pyrrolidinone with elemental iodine. The povidone component serves the function of iodide in aqueous iodine solutions and tinctures, which is to increase the solubility and to provide a slow release form of iodine.

Advantages

As compared to iodine solutions and tinctures, PVP solutions offer the following advantages:

• Prolonged Action- By liberating elemental iodine more slowly, povidone iodine solution has prolonged antimicrobial activity.
• Less Irritating- Since the concentration of free iodine in PVP solutions is lower, povidone iodine solutions are less irritating, particularly under occlusive dressings.
• Nonstaining- PVP solutions stain the skin and clothing less than iodine solutions and tinctures.

Indications

PVP Topical solutions retain the broad spectrum antimicrobial and antiviral activity of iodine. It is used for the prevention of infection in minor burns, abrasions and cuts and in the preparation of the skin for injection and hyperalimentation procedures.

Product Stability

James Alexander’s Povidone iodine USP swabs carry a five (5) year expiration date, the maximum amount allowed by the Food and Drug Administration.

Directions For Use

Reverse cardboard sleeve on swab. Crush ONCE between the thumb and forefinger at the dot located at the center of the swab. Gently squeeze swab to apply to the desired area. To avoid glass splinters, use only with paper cap completely in place.

James Alexander’s Product Configuration and Packaging

James Alexander offers PVP Topical Solution USP as a 10% solution packaged in unit dose swab containing 0.6 mls of solution.

• James Alexander Product Code G-7702- Bulk swabs, packaged 5,000 per shipping carton.
• James Alexander Product Code 773- Unit dose swabs packaged 10 per box.
• James Alexander Product Code 772- Unit dose swabs packaged 100 per box.

Pricing | Drug Facts

Product Description

Compound Benzoin Tincture USP (CBT) is a botanical product derived from plants of the family Styraceae. Benzoin producing plants are small to medium trees growing in tropical Asia. Benzoin is a pathological product formed when the tree trunk is injured. It is produced by incising the bark and collecting the exuded resin after it hardens on exposure to air and light. Benzoin is an ancient drug that has had more different Latin titles and synonyms since its origin in the 15th or 16th century than any other official preparation. Benzoin contains esters of cinnamic and benzoic acids together with free acids. Amounts and types of esters vary with its source. CBT is prepared by mixing benzoin with aloe, storax, and Tolu Balsam. Alcohol is used as the menstruum.

Indications

• Skin Protectant- CBT is widely used as a skin protectant, and is particularly effective for ulcers, bedsores, cracked nipples, and fissures of the lips and anus.
• Respiratory Treatment- CBT relieves respiratory discomforts when added to vaporizer fluids used for inhalation.
• Dental Uses- CBT is used in dentistry to treat oral herpetic lesions and inflammation of the gums.

Product Stability

James Alexander’s Compound Benzoin Tincture USP swabs carry a five (5) year expiration date, the maximum allowed by the Food and Drug Administration.

Directions for Use

Reverse cardboard sleeve on swab. Crush ONCE between the thumb and forefinger at the dot located at the center of the swab. Gently squeeze swab to apply to the desired area. To avoid glass splinters, use only with paper cap completely in place.

James Alexander Product Configuration and Packaging

JAC offers Compound Benzoin Tincture USP as a unit dose swab containing 0.6 mls of solution.

• James Alexander Code G-88 – bulk unit dose Compound Benzoin Tincture USP swabs packaged 5,000 units per shipping carton.
• James Alexander Product Code 882 – unit dose swabs packaged 100 per box.

Pricing | Drug Facts

Product Description

Medicaine^® Sting and Bite Relief is a James Alexander Corporation proprietary formulation that provides relief of pain and itching associated with insect bites and stings.

Active Ingredients

Medicaine^® Sting and Bite Relief was developed in accordance with the Food and Drug Administration’s proposed rules for over-the counter topical analgesic drug products and contains two active ingredients (menthol and benzocaine) in the maximum allowable concentrations:

• Benzocaine – An advisory panel investigating external analgesic drug products for the FDA called benzocaine “one of the most widely used and safest topical anesthetics found in OTC preparations.” Benzocaine acts by blocking nerve and pain receptors.
• Menthol – According to the FDA Panel, “When applied to the skin, menthol stimulates the nerves for the perception of cold, while depressing those which perceive pain.”

James Alexander has combined these two highly effective active ingredients in a water soluble base that assures the formulation’s effectiveness.

Product Stability

James Alexander’s Medicaine^® Sting and Bite Relief Formulation swabs carry a five (5) year expiration date, the maximum allowed by the Food and Drug Administration.

Directions For Use

Reverse cardboard sleeve on swab. Crush ONCE between the thumb and forefinger at the dot located at the center of the swab. Gently squeeze swab to apply to the desired area. To avoid glass splinters, use only with paper cap completely in place. Caution: Do not use in the eyes. Not for prolonged use. If the pain or itching associated with the bite or sting persists or if swelling develops, discontinue use and consult a physician.

James Alexander’s Product Configuration and Packaging

James Alexander offers Medicaine^® Sting and Bite Relief Formulation as a unit dose swab containing 0.6 mls of solution.

• James Alexander Product Code G-2042- Bulk swabs, packaged 10,000 per shipping carton.
• James Alexander Product Code 2043- unit dose swabs packaged 10 per box (designed for use in first aid kits).

Safety Data Sheet | Pricing | Drug Facts